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STEMCELL Technologies Human Recombinant IL-11, ACF
Interleukin 11, animal component-free
Brand: STEMCELL Technologies 78192
Additional Details : Weight : 0.00110kg
Description
- Interleukin 11 (IL-11) is a pleiotropic cytokine with effects on various tissues including the bone marrow, brain, and intestinal mucosa
- It belongs to the IL-6 family of cytokines that share a common signal transducer, gp130
- IL-11 induces the proliferation of hematopoietic stem cells and megakaryocytic progenitor cells, the maturation of megakaryocytes, and the production of platelets
- IL-11 is produced by a variety of cell types including hematopoietic cells, mesenchymal cells, epithelial cells, and neuronal cells
- It was first cloned from a cDNA library of the human bone marrow-derived stromal cell line KM-102
- The binding of IL-11 to its receptor induces heterodimerization with the gp130 subunit and activation of JAK tyrosine kinases
- This product is animal component-free
Specifications
| Adipogenesis inhibitory factor, AGIF, Interleukin-11, Oprelvekin | |
| ≥95% | |
| 10 μg | |
| B Cells; Hematopoietic Stem and Progenitor Cells; Other; Pluripotent Stem Cells; T Cells |