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STEMCELL Technologies Human Recombinant IL-11, ACF
Interleukin 11, animal component-free
Specifications
Cell Type | B Cells; Hematopoietic Stem and Progenitor Cells; Other; Pluripotent Stem Cells; T Cells |
---|---|
Purity or Quality Grade | ≥95% |
Description
- Interleukin 11 (IL-11) is a pleiotropic cytokine with effects on various tissues including the bone marrow, brain, and intestinal mucosa
- It belongs to the IL-6 family of cytokines that share a common signal transducer, gp130
- IL-11 induces the proliferation of hematopoietic stem cells and megakaryocytic progenitor cells, the maturation of megakaryocytes, and the production of platelets
- IL-11 is produced by a variety of cell types including hematopoietic cells, mesenchymal cells, epithelial cells, and neuronal cells
- It was first cloned from a cDNA library of the human bone marrow-derived stromal cell line KM-102
- The binding of IL-11 to its receptor induces heterodimerization with the gp130 subunit and activation of JAK tyrosine kinases
- This product is animal component-free
Specifications
B Cells; Hematopoietic Stem and Progenitor Cells; Other; Pluripotent Stem Cells; T Cells | |
≥95% |
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Product Title
STEMCELL Technologies Human Recombinant IL-11, ACF