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Invitrogen™ VEGF Receptor 3/FLT4 Human ELISA Kit

For the quantitative detection of human VEGF-R3/FLT-4.

Brand:  Invitrogen™ BMS2064TEN

Additional Details : Weight : 0.23750kg

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Product Code. 15561577

  • 30380.00 SEK / Pack of 10


Estimated Shipment
09-12-2020
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Includes: Aluminium pouch(es) with a Microwell Plate coated with monoclonal antibody to human VEGF-R3/FLT-4
Biotin-Conjugate anti-human VEGF-R3/FLT-4 monoclonal antibody
Streptavidin-HRP
Human VEGF-R3/FLT-4 Standard lyophilized, 80ng/mL upon reconstitution
Sample Diluent
Assay Buffer Concentrate 20x (PBS with 1% Tween 20 and 10% BSA)
Wash Buffer Concentrate 20x (PBS with 1% Tween 20)
Substrate Solution (tetramethyl-benzidine)
Stop Solution (1M Phosphoric acid)
Blue-Dye
Green-Dye
Red-Dye
Adhesive Films

Description

Description

The main function of the lymphatic system is to return plasma back to the circulating blood. Plasma fluid, macromolecules and cells, such as leucocytes and activated antigen-presenting cells, enter the blind-ended lymphatic vessels. Lymph is then transported toward collecting lymphatic vessels and is returned to the blood circulation. Scientific studies over the past years have revealed a signal-transduction system for lymphatic endothelial cell growth, migration and survival. This system is formed by VEGF-C and VEGF-D and their shared receptor VEGFR-3/FLT-4. Homozygous deletion of VEGFR-3 in mice leads to defects in blood-vessel remodelling and embryonic death at mid-gestation, indicating an early vascular function for the receptor. Furthermore mouse studies suggest that upregulation and activation of VEGFR-3 have functional roles in sprouting angiogenesis and that VEGFR-3 is an important effector of the vascular phenotype resulting from Notch inhibition. In lymphoma patients, high expression of VEGFR-3 can been found in lymph endothelial cells isolated from the tumour tissue.
Specifications

Specifications

P35916
Biotin
2324
ELISA Kit
0.03 ng/mL
Plasma, 20 μL|Serum, 20 μL|Supernatant, 20 μL
1 hr. 20 min.
Human
FLT-4, VEGF receptor 3, PCL
5.7%
Human
HRP
0.6-40.0 ng/mL
ELISA
Pre-coated 96 well plate, Standard, Sample Diluent, Assay Buffer concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
RUO
50 μL (1:10 prediluted)
2°C to 8°C
3 hr. 30 min.
FLT-41,LMPH1A,PCL,VEGFR-3,VEGFR3,FLT4
5%
10 x 96 Tests
Supernatant
Colorimetric Microplate Reader
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For Research Use Only