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ID3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

1656.73 SEK - 4721.67 SEK

Specifications

Antigen ID3
Concentration 0.4 mg/mL
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16886743
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Proteintech
10389-1-AP-20UL
20 μL
1656.73 SEK
20µL
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Estimated Shipment: 02-04-2024
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16876743
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Proteintech
10389-1-AP-150UL
150 μL
4721.67 SEK
150µL
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Estimated Shipment: 02-04-2024
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Description

Description

Members of the Id family of basic helix-loop-helix (bHLH) proteins include ID1, ID2, ID3 and ID4. They are ubiquitously expressed and dimerize with members of the class A and B HLH proteins. Due to the absence of the basic region, the resulting heterodimers cannot bind DNA. The ID-type proteins thus appear to negatively regulate DNA binding of bHLH proteins. Since ID1 inhibits DNA binding of E12 and Myo D, it apparently functions to inhibit muscle-specific gene expression. Under conditions that facilitate muscle cell differentiation, the ID protein levels fall, allowing E12 and/or E47 to form heterodimers with Myo D and myogenin, which in turn activate myogenic differentiation. It has been shown that expression of each of the ID proteins is strongly dependent on growth factor activation and that reduction of ID mRNA levels by antisense oligonucleotides leads to a delayed reentry of arrested cells into the cell cycle following growth factor stimulation.
Specifications

Specifications

ID3
Western Blot
Unconjugated
Rabbit
Mouse, Human, Rat
P41133, P41138, Q02535
15903, 25585, 3399
ID3 Fusion Protein Ag0588
Primary
-20°C
ID3
0.4 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
1R21, bHLHb25, HEIR 1, HEIR1, ID3, Inhibitor of DNA binding 3
ID3
IgG
Antigen Affinity Chromatography
Antibody
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SDS
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