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IDO1 Mouse anti-Human, Mouse, Rat, Clone: 3G2G11, Proteintech
Mouse Monoclonal Antibody
1656.73 SEK - 4721.67 SEK
Specifications
Antigen | IDO1 |
---|---|
Clone | 3G2G11 |
Concentration | 1 mg/mL |
Applications | Western Blot |
Classification | Monoclonal |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
16888485
|
Proteintech
66528-1-IG-20UL |
20 μL |
1656.73 SEK
20µL |
Estimated Shipment: 19-04-2024 Log in to see stock. |
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16878485
|
Proteintech
66528-1-IG-150UL |
150 μL |
4721.67 SEK
150µL |
Estimated Shipment: 19-04-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
IDO1 is an intracellular heme-containing enzyme that catalyzes the oxidative cleavage of the indole ring of several important regulatory molecules like tryptophan, serotonin, and melatonin. By doing this, IDO1 initiates the production of biologically active metabolites, commonly referred to as kynurenines. IDO1 is widely expressed in a variety of human tissues as well as in macrophages and dendritic cells (DCs). In inflammation, interferons (IFNs) act on specific receptors to trigger IDO1 induction. The production of IFN-gamma and induction of IDO1 represent important antimicrobial mechanisms. Degradation and depletion of tryptophan by IDO1 inhibits the growth of viruses, bacteria and parasites. Furthermore, IDO1 plays a complex and crucial role in immunoregulation during infection, pregcy, autoimmunity, transplantation, and neoplasia.Specifications
IDO1 | |
1 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
CD107B, IDO, IDO 1, IDO1, INDO, indoleamine 2,3 dioxygenase 1 | |
Ido1 | |
IgG1 | |
Protein G | |
Antibody |
3G2G11 | |
Western Blot | |
Unconjugated | |
Mouse | |
Human, Rat, Mouse | |
P14902, P28776, Q9ERD9 | |
15930, 3620, 66029 | |
IDO1 Fusion Protein Ag3953 | |
Primary | |
-20°C | |
IDO1 |