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IL-23 p19 Mouse anti-Human, Functional Grade, Clone: HNU2319, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 16-5236-85

Additional Details : Weight : 0.01000kg

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Product Code. 15208647

  • 2510.00 SEK / 500µg


Estimated Shipment
29-09-2020
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Description

Description

This antibody is specific to the p19 subunit of IL-23, and will not affect the bioactivity of IL-12. The neutralization dose of this antibody will vary depending on cell type, assay method, and concentration of cytokine. Endotoxin: Less than 0.001 ng/ug antibody as determined by the LAL assay. Storage and handling: Use in a sterile environment. Filtration: 0.2 μm post-manufacturing filtered. Purity: Greater than 90%, as determined by SDS-PAGE. Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay. Aggregation: Less than 10%, as determined by HPLC. This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity.
Specifications

Specifications

IL-23 p19
Monoclonal
1 mg/mL
PBS with no preservative; pH 7.2
Q9NPF7
IL-23, IL-23A, IL23P19, MGC79388, P19, SGRF
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Functional Assay, Neutralization
HNU2319
Functional Grade
IL23A
Liquid
IL23A
IgG1, kappa
500 μg
4° C
Primary
51561
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