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INSR Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 20433-1-AP-150UL
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Description
The insulin receptor (IR) is a heterodimeric protein complex that has an intracellular beta subunit and an extracellular alpha subunit, which is disulfide- linked to a transmembrane segment. The insulin ligand binds to the IR and initiates molecular signaling pathways that promote glucose uptake in cells and glycogen synthesis. Insulin binding to IR induces phosphorylation of intracellular tyrosine kinase domains and recruitment of multiple SH2 and SH3 domain-containing intracellular proteins that serve as signaling intermediates for pleiotropic effects of insulin.Specifications
| INSR | |
| Polyclonal | |
| Unconjugated | |
| INSR | |
| CD220, HHF5, INSR, insulin receptor, IR | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 3643 | |
| -20°C | |
| Liquid |
| Immunoprecipitation, Western Blot | |
| 0.25 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| P06213 | |
| INSR | |
| INSR Fusion Protein Ag13922 | |
| 150 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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Product Title
INSR Rabbit anti-Human, Polyclonal, Proteintech > 150 μL; Unconjugated
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