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Integrin beta-7 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 11328-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16888323

  • 1656.73 SEK / 20µL
Estimated Shipment: 03-04-2024
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Description

Description

Integrin beta 7 associates with integrin alpha 4 (CD49d) to form the alpha 4 beta 7 integrin LPAM-1, expressed on intraepithelial lymphocytes. It also associates with alpha E (CD103) to form the alpha E beta 7 integrin HML-1, expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes. Ligands for LPAM-1 include VCAM-1 (CD106), MAdCAM-1 and fibronectin, while the ligand of HML-1 is E-cadherin (CD324). Integrin beta 7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response.
Specifications

Specifications

Integrin beta-7
Polyclonal
Unconjugated
ITGB7
Integrin beta 7, integrin, beta 7, ITGB7
Rabbit
Antigen Affinity Chromatography
RUO
16421, 25713, 3695
-20°C
Liquid
Immunohistochemistry (Paraffin), Western Blot
0.3 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P26010, P26011
ITGB7
Integrin beta-7 Fusion Protein Ag1871
20 μL
Primary
Human, Rat, Mouse
Antibody
IgG
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