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IRF8 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
1656.73 SEK - 4721.67 SEK
Specifications
Antigen | IRF8 |
---|---|
Concentration | 0.34 mg/mL |
Applications | Western Blot |
Classification | Polyclonal |
Conjugate | Unconjugated |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
16882915
|
Proteintech
24437-1-AP-20UL |
20 μL |
1656.73 SEK
20µL |
Estimated Shipment: 22-04-2024 Log in to see stock. |
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16872915
|
Proteintech
24437-1-AP-150UL |
150 μL |
4721.67 SEK
150µL |
Estimated Shipment: 22-04-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
This antibody specifically recognizes the 48 kDa IRF8 protein.
IRF8 (interferon regulatory factor 8) is a transcriptional activator or repressor. It specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes. IRF8 plays a negative regulatory role in cells of the immune system. It is involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells. This leads to recognition of AICE sequence, an immune-specific regulatory element, followed by cooperative binding of BATF and IRF8 and activation of the genes. Mutations in the gene can result in immunodeficiencey 32A and 32B.Specifications
IRF8 | |
Western Blot | |
Unconjugated | |
Rabbit | |
Human | |
Q02556 | |
3394 | |
IRF8 Fusion Protein Ag19909 | |
Primary | |
-20°C | |
IRF8 |
0.34 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
H ICSBP, ICSBP, ICSBP1, interferon regulatory factor 8, IRF 8, IRF8 | |
IRF8 | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |