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IRF8 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

1645.54 SEK - 4652.90 SEK

Specifications

Antigen	IRF8
Concentration	0.34 mg/mL
Applications	Western Blot
Classification	Polyclonal
Conjugate	Unconjugated

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Products 2

Product Code	Brand	Quantity	Price	Quantity & Availability
Product Code	Brand	Quantity	Price	Quantity & Availability
16882915 View Documents missing translation for 'viewProductCertificates'	Proteintech 24437-1-AP-20UL	20 μL	1645.54 SEK 20µL		Please sign in to purchase this item. Need a web account? Register with us today!

16872915 View Documents missing translation for 'viewProductCertificates'	Proteintech 24437-1-AP-150UL	150 μL	4652.90 SEK 150µL		Please sign in to purchase this item. Need a web account? Register with us today!

Description

This antibody specifically recognizes the 48 kDa IRF8 protein.

IRF8 (interferon regulatory factor 8) is a transcriptional activator or repressor. It specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes. IRF8 plays a negative regulatory role in cells of the immune system. It is involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells. This leads to recognition of AICE sequence, an immune-specific regulatory element, followed by cooperative binding of BATF and IRF8 and activation of the genes. Mutations in the gene can result in immunodeficiencey 32A and 32B.

Specifications

Antigen	IRF8
Applications	Western Blot
Conjugate	Unconjugated
Host Species	Rabbit
Target Species	Human
Gene Accession No.	Q02556
Gene ID (Entrez)	3394
Immunogen	IRF8 Fusion Protein Ag19909
Primary or Secondary	Primary
Content And Storage	-20°C
Gene	IRF8

Concentration	0.34 mg/mL
Classification	Polyclonal
Form	Liquid
Regulatory Status	RUO
Formulation	PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Alias	H ICSBP, ICSBP, ICSBP1, interferon regulatory factor 8, IRF 8, IRF8
Gene Symbols	IRF8
Isotype	IgG
Purification Method	Antigen Affinity Chromatography
Product Type	Antibody

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IRF8 Rabbit anti-Human, Polyclonal, Proteintech

Specifications

Description

Specifications

Documents