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ITCH Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 20920-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16840505

  • 3313.85 SEK / 150µL
Estimated Shipment: 05-10-2022
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Description

Description

Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. The protein encoded by this gene interacts with atrophin-1. This encoded protein is a closely related member of the NEDD4-like protein family. This family of proteins are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. This encoded protein contains four tandem WW domains and a HECT domain. It can act as a transcriptional corepressor of p45/NFE2 and may participate in the regulation of immune responses by modifying Notch-mediated signaling. It is highly similar to the mouse Itch protein, which has been implicated in the regulation and differentiation of erythroid and lymphoid cells.
Specifications

Specifications

ITCH
Polyclonal
Unconjugated
ITCH
AIF4, AIP4, ITCH, NAPP1, NFE2 associated polypeptide 1
Rabbit
Antigen Affinity Chromatography
RUO
16396, 83737
-20°C
Liquid
Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin)
0.23 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q8C863, Q96J02
ITCH
ITCH Fusion Protein Ag15120
150 μL
Primary
Mouse, Human
Antibody
IgG
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