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ITGA6X1A Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 20231-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16839754

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Description

Description

E3 ubiquitin-protein ligase that mediates the ubiquitination of p53/TP53 in the late response to DNA damage, and acts as a positive regulator of p53/TP53 stability, thereby regulating the G1/S DNA damage checkpoint. May act by catalyzing the formation of short polyubiquitin chains on p53/TP53 that are not targeted to the proteasome. In response to ionizing radiation, interacts with MDM2 and enhances p53/TP53 ubiquitination, possibly by restricting MDM2 from extending polyubiquitin chains on ubiquitinated p53/TP53. Plays a role in RPA-mediated DNA damage signaling and repair.
Specifications

Specifications

ITGA6X1A
Polyclonal
Unconjugated
ITGA6
CD49f, Integrin alpha 6, integrin, alpha 6, ITGA6, ITGA6B, VLA 6
Rabbit
Antigen Affinity Chromatography
RUO
16403, 3655
-20°C
Liquid
Western Blot
0.17 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P23229, Q61739
Itga6
Peptide
20 μL
Primary
Mouse, Human
Antibody
IgG
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SDS
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Documents

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Special Offers

Special Offers