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JAML Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 21302-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16880905

  • 4721.67 SEK / 150µL
Estimated Shipment: 02-04-2024
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Description

Description

AMICA transmembrane protein of the plasma membrane of leukocytes that control their migration and activation through interaction with CXADR, a plasma membrane receptor found on adjacent epithelial and endothelial cells. The interaction between both receptors mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair. It also controls the transmigration of leukocytes within epithelial and endothelial tissues through adhesive interactions with epithelial and endothelial CXADR.
Specifications

Specifications

JAML
Polyclonal
Unconjugated
JAML
AMICA, AMICA1, CREA7 1, CREA7 4, Gm638, JAML
Rabbit
Antigen Affinity Chromatography
RUO
120425
-20°C
Liquid
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
0.33 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q86YT9
JAML
JAML Fusion Protein Ag15900
150 μL
Primary
Human
Antibody
IgG
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