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JIP1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
1645.54 SEK - 4652.90 SEK
Specifications
| Antigen | JIP1 |
|---|---|
| Concentration | 0.3 mg/mL |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Immunofluorescence |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
16883264
|
Proteintech
14568-1-AP-20UL |
20 ÎĽL |
1645.54 SEK
20µL |
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|
16873264
|
Proteintech
14568-1-AP-150UL |
150 ÎĽL |
4652.90 SEK
150µL |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
The protein encoded by this gene is a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2. RE1-silencing transcription factor (REST) is reported to repress the expression of this gene in insulin-secreting beta cells. This gene is found to be mutated in a type 2 diabetes family, and thus is thought to be a susceptibility gene for type 2 diabetes.Specifications
| JIP1 | |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Immunofluorescence | |
| Unconjugated | |
| Rabbit | |
| Mouse, Rat, Human | |
| Q9R237, Q9UQF2, Q9WVI9 | |
| 116457, 19099, 9479 | |
| JIP1 Fusion Protein Ag6150 | |
| Primary | |
| -20°C | |
| MAPK8IP1 |
| 0.3 mg/mL | |
| Polyclonal | |
| Liquid | |
| RUO | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| IB 1, IB1, Islet brain 1, JIP 1, JIP1, JNK interacting protein 1, MAPK8IP1, PRKM8IP | |
| Mapk8ip1 | |
| IgG | |
| Antigen Affinity Chromatography | |
| Antibody |
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Product Title
JIP1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech