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KI67 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 27309-1-AP-20UL
Additional Details : Weight : 0.00010kg
Description
Ki-67 is a nuclear protein that is expressed during various stages in the cell cycle, particularly during late G1, S, G2, and M phases. The protein has a forkhead associated domain (FHA) through which it associates with euchromatin at the perichromosomal layer, the centromeric heterochromatin, and the nucleolus. Ki-67 is shown to have a cell cycle dependent topographical distribution with perinucleolar expression at G1, expression in the nuclear matrix at G2, and expression on the chromosomes during M phase. Ki-67 is commonly used as a proliferation marker because it is not detected in G0 cells, but increases steadily from G1 through mitosis. Ki-67 antibodies are useful in establishing the cell growing fraction in neoplasms. In neoplastic tissues, the prognostic value is comparable to the tritiated thymidine-labelling index. The correlation between low Ki-67 index and histologically low-grade tumors is strong. Ki-67 is routinely used as a neuronal marker of cell cycling and proliferation.Specifications
KI67 | |
Polyclonal | |
Unconjugated | |
MKI67 | |
Antigen KI 67, Ki 67, KI67, KIA, MKI67 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
4288 | |
-20°C | |
Liquid |
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin) | |
0.6 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
P46013 | |
MKI67 | |
KI67 Fusion Protein Ag26266 | |
20 μL | |
Primary | |
Human | |
Antibody | |
IgG |