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L-Plastin Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 55208-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16886695

  • 1236.20 SEK / 20µL
Estimated Shipment: 30-11-2021

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Description

Description

L-plastin is a leukocyte specific actin bundling protein from fimbrin family of proteins. It has two actin-binding domains and two EF hand type calcium-binding domains. It gets phosphorylated on the serine residue in its headpiece region in response to a variety of inflammatory stimuli. It is hypothesized that L-plastin may play a role in regulating integrin mediated adhesion in leukocytes. L-plastin is expressed in majority of human cancer cell lines derived from solid tumors. Its expression is positively upregulated by testosteronse in andrgen receptor positive prostrate and breast cancer cells through three androgen receptor binding elements located in the upstream region of the gene.
Specifications

Specifications

L-Plastin
0.5 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P13796, Q61233
L PLASTIN, LCP 1, LCP1, LPL, Lymphocyte cytosolic protein 1, Plastin 2, PLS2
Rabbit
IgG
20 μL
-20°C
Primary
18826, 3936
Immunofluorescence, Western Blot, Immunocytochemistry
Unconjugated
LCP1
Liquid
Lcp1
Peptide
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Mouse, Human
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