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LDLR Mouse anti-Human, Clone: 1A2A3, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 66414-1-IG-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16888265

  • 3313.85 SEK / 150µL
Estimated Shipment: 07-12-2021

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Description

Description

The low density lipoprotein (LDL) receptor system coordinates the metabolism of cholesterol, an essential component of the plasma membrane of all mammalian cells. Study of this system has led to an enhanced understanding of the cellular basis of cholesterol homeostasis. It has also brought into focus an important mechanism of metabolic regulation-the process of receptor-mediated endocytosis. Data suggest that the juxtamembranous region of the cytoplasmic domain participates in protein:protein interactions that allow the low density lipoprotein receptor to cluster in coated pits. It has been shown that the family of LDL receptors may serve as viral receptors. Endocytosis of the Flaviviridae viruses, hepatitis C virus, GB virus C/hepatitis G virus, and bovine viral diarrheal virus (BVDV) was shown to be mediated by LDL receptors on cultured cells.
Specifications

Specifications

LDLR
1A2A3
Unconjugated
LDLR
Liquid
LDLR
LDLR Fusion Protein Ag1236
Protein G
RUO
Antibody
Monoclonal
Human
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P01130
FH, FHC, LDL receptor, LDLR
Mouse
IgG1
150 μL
-20°C
Primary
3949
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