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LIN28 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 11724-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16828993

  • 3313.85 SEK / 150µL
Estimated Shipment: 02-12-2021

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Description

Description

This antibody is a rabbit polyclonal antibody raised against full length LIN28 of human origin. The calculated molecular weight of LIN28 is 23 kDa, but the modified LIN28 is about 28 kDa.

Lin28 is a transcription factor that was first identified through its key role in the pathway of developmental timing in C. elegans. The role of Lin28 in development suggested that it might be useful in the creation of stem cells that might be beneficial in cell replacement therapies in the treatment of several degenerative diseases. Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing Lin28 in addition to the transcription factors POU5F1, Sox2, and NANOG in mouse fibroblasts. More recently, experiments have demonstrated that iPS cells could be generated using expression plasmids expressing Lin28, Sox2, POU5F1 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine.
Specifications

Specifications

LIN28
0.31 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q8K3Y3, Q9H9Z2
CSDD1, LIN 28, lin 28 homolog (C. elegans), Lin 28A, LIN28, Lin28A, Protein lin 28 homolog A, ZCCHC1
Rabbit
IgG
150 μL
-20°C
Primary
500562, 79727, 83557
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
LIN28A
Liquid
Lin28a
LIN28 Fusion Protein Ag2312
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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