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LMP7 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 14859-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16883724

  • 1656.73 SEK / 20µL
Estimated Shipment: 03-04-2024
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Description

Description

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 3 (proteasome beta 5 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. Two alternative transcripts encoding two isoforms have been identified; both isoforms are processed to yield the same mature subunit.
Specifications

Specifications

LMP7
Polyclonal
Unconjugated
PSMB8
beta5i, D6S216, D6S216E, LMP7, Low molecular mass protein 7, Macropain subunit C13, Proteasome component C13, Proteasome subunit beta 5i, Proteasome subunit beta type 8, PSMB5i, PSMB8, RING10, Y2
Rabbit
Antigen Affinity Chromatography
RUO
16913, 5696
-20°C
Liquid
Immunohistochemistry (Paraffin), Immunocytochemistry, Immunofluorescence, Flow Cytometry, Immunoprecipitation
0.31 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P28062, P28063
Psmb8
LMP7 Fusion Protein Ag6660
20 μL
Primary
Human, Mouse
Antibody
IgG
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