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Lovastatin, 97%, Thermo Scientific™

1179.56 SEK - 4328.76 SEK

Kemiska identifierare

CAS 75330-75-5
Molekylformel C24H36O5
Molekylvikt (g/mol) 404.55
MDL-nummer MFCD00072164
InChI-nyckel PCZOHLXUXFIOCF-BXMDZJJMSA-N
Synonym lovastatin, mevinolin, mevacor, monacolin k, lovalip, altoprev, lovalord, mevinacor, nergadan, 6alpha-methylcompactin
PubChem CID 53232
ChEBI CHEBI:40303
IUPAC-namn (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate
LEDER CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12
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Produkter 2
Produktkod Brand Kvantitet Pris Kvantitet och tillgänglighet  
Produktkod Brand Kvantitet Pris Kvantitet och tillgänglighet  
15489537
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Thermo Scientific Alfa Aesar
H52792.06 		5g
1179.56 SEK
5g
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15499537
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Thermo Scientific Alfa Aesar
H52792.14 		25g
4328.76 SEK
25g
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Spara upp till  »
Vänligen för att beställa denna produkten. Behöver du ett Webbkonto? Registrera ditt konto idag!
Beskrivning

Beskrivning

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

Applications
Lovastatin is a cholesterol lowering drug and competitive inhibitor of HMG-CoA reductase, a rate limiting enzyme in cholesterol synthesis. Blocks the production of mevalonate, a critical compound in the production of cholesterol and isoprenoids. It increases cellular resistance to anticancer agents such as doxorubicin and induces apoptosis in myeloma cells. It causes cell cycle arrest in G1 and G2/M phases.

Solubility
Soluble in DMSO (10 mg/ml), ethanol (10 mg/ml), methanol, chloroform, acetone, acetonitrile, DMF, and water (0.4 µg/ml).

Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents and heat.
Specifikationer

Kemiska identifierare

75330-75-5
404.55
PCZOHLXUXFIOCF-BXMDZJJMSA-N
53232
(1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate
C24H36O5
MFCD00072164
lovastatin, mevinolin, mevacor, monacolin k, lovalip, altoprev, lovalord, mevinacor, nergadan, 6alpha-methylcompactin
CHEBI:40303
CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12

Specifikationer

Lovastatin
C24H36O5
lovastatin, mevinolin, mevacor, monacolin k, lovalip, altoprev, lovalord, mevinacor, nergadan, 6alpha-methylcompactin
PCZOHLXUXFIOCF-BXMDZJJMSA-N
(1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate
53232
404.56
75330-75-5
MFCD00072164
Soluble in DMSO (10mg/ml),ethanol (10mg/ml),methanol,chloroform,acetone,acetonitrile,DMF,and water (0.4 μg/ml).
CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12
404.55
CHEBI:40303
97%
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Säkerhet och hantering

Säkerhet och hantering

GHS H Statement
H302-H315-H319-H335
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

P201-P202-P261-P272-P280g-P281-P302+P352-P308+P313-P333+P313-P363-P501c

H317-H351-H361d

missing translation for 'rtecsNumber' : EK7907000

missing translation for 'tsca' : No

Rekommenderad förvaring : Ambient temperatures

SDS
Dokument

Dokument

Produktspecifikationer

RUO – Research Use Only

Produkttitel
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