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LRAT Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 12815-1-AP-150UL
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Description
This antibody was generated against the internal residues of human LRAT. It is predicted to detect endogenous LRAT.
Lecithin retinol acyltransferase (LRAT) is a membrane bound enzyme that catalyzes the transfer of an acyl group from the sn-1 position of lecithin to vitamin A which generates all-trans-retinyl esters (tREs) in the liver, some extrahepatic tissues, such as the lung, and retinal pigmented epithelium. LRAT can also exchange palmitoyl groups between RPE65, a tRE binding protein essential for vision, and tREs, which is important for the operation of the visual pathway. LRAT is essential for the dietary mobilization, transport, and storage of vitamin A as well as the synthesis of the visual pigment chromophore. LRAT monomers interact in membranes to form homodimers through disulfide bond formation. A loss of LRAT correlates with an early onset severe retinal dystrophy and severe retinyl ester deprivation, while a reduction in LRAT expression may be associated with invasive bladder cancer.Specifications
LRAT | |
Polyclonal | |
Unconjugated | |
LRAT | |
LRAT | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
64047, 79235, 9227 | |
-20°C | |
Liquid |
Western Blot | |
0.27 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
O95237, Q9JI60, Q9JI61 | |
Lrat | |
LRAT Fusion Protein Ag3556 | |
150 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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Product Title
LRAT Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech > 150 μL; Unconjugated
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