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Invitrogen™ Human MAP3K11 (MLK3), GST Tag Recombinant Protein

Product Code. p-7121796
100 μg, 100µg
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Quantity:
1 mg
10 μg
100 μg
Unit Size:
100µg
10µg
1mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Recombinant, Full Length

MAP3K11 (MLK3) is a serine/threonine kinase that activates both the p38 MAP kinase and c-Jun kinase pathways. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q16584
Concentration See Label
For Use With (Application) Kinase Assay
Formulation 50 mM tris with 0.02% Triton X-100, 0.5 mM EDTA, 150 mM NaCl, 2 mM DTT, 50% glycerol and no preservative; pH 7.5
Gene ID (Entrez) 4296
Molecular Weight (g/mol) 120.1 kDa
Name Human MAP3K11 (MLK3), GST Tag
Quantity 100 μg
Source Human
Gene Alias 2610017K16Rik; MAP3K11; MEKK11; MGC17114; mitogen activated protein kinase kinase kinase 11; mitogen-activated protein kinase kinase kinase 11; Mixed lineage kinase 3; Mlk3; MLK-3; protein-tyrosine kinase PTK1; PTK1; RHOE; SH3 domain-containing proline-rich kinase; SPRK; Src-homology 3 domain-containing proline-rich kinase
Common Name MLK3
KinaseFamily MLK Kinase Family
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag GST-tag
Sequence Full length
Content And Storage -80°C, Avoid Freeze/Thaw Cycles
Kinase Group Ser⁄Thr Kinases: TKL Group
Shipping Condition Dry Ice
Expression System Insect cells
Protein Family Kinases & Inhibitors
Protein Form Recombinant, Full Length
Form Liquid
Protein Subtype Serine/Threonine Kinases
Research Category Immunology, Oncology, Signal Transduction
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