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MASH1 Mouse anti-Mouse, Rat, Clone: 24B72D11, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-5794-82

Additional Details : Weight : 0.09500kg

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Product Code. 15557456

  • 2590.00 SEK / 100µg


In stock, ready to ship: 1
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Description

Description

It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 µm post-manufacturing filtered. ASCL1 (also known as ASH1) is a basic helix-loop-helix transcription factor that is required for early development of the nervous system. Expressed in fetal brain, ASCL1 is essential for the proper development of autonomic neurons and for the survival of subsets of autonomic neurons. ASCL1 interaction with MEF-2A may regulate the expression of specific genes that are critical for the formation of distinct neuronal circuits within the central nervous system. The high level of ASCL1 expression in neuroendocrine tumors, such as medullary thyroid cancer, small cell lung cancer and lung cancer with neuroendocrine features may provide a useful marker for cancers with neuroendocrine features. Mapping to human chromosome 12, the ASCL1 gene contains a trinucleotide repeat region, making this locus a candidate for inherited disease.
Specifications

Specifications

MASH1
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P19359, Q02067
KMT2H
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen), Western Blot
24B72D11
Unconjugated
Ascl1
Liquid
Ascl1
IgG1, kappa
100 μg
4° C
Primary
17172, 64186
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For Research Use Only.