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Gibco™ Mouse CXCL12 (SDF-1b) Recombinant Protein
Recombinant Protein
Brand: Gibco™ PMC1364
This item is not returnable.
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Description
Carrier-Free Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile, distilled water to a concentration of 0.1-1.0 mg/mL. Further dilutions should be made in aqueous buffers supplemented with carrier protein, such as 0.1-1.0% BSA. Storage: This lyophilized preparation is stable at 2°C to 8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2°C to 8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C. Avoid repeated freeze/thaw cycles.
CXCL12 is a stromal cell-derived alpha chemokine member of the intercrine family. This gene product and its receptor CXCR4 can activate lymphocytes and have been implicated in the metastasis of some cancers such as breast cancer. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.
Specifications
| P40224 | |
| protein with no preservative | |
| 8.5 kDa | |
| Sequential Chromatography | |
| <0.1 ng/ μg | |
| CXCL12 | |
| Unconjugated | |
| Recombinant | |
| -20°C | |
| <0.1 ng/μg | |
| E. coli | |
| Recombinant, Ligand | |
| SDFs (Stromal Cell-Derived Factors) | |
| Gibco™ |
| Control, ELISA, Functional Assay, Immunohistochemistry, Western Blot | |
| 20315 | |
| Mouse CXCL12 (SDF-1 b) | |
| 10 μg | |
| 12-O-tetradecanoylphorbol 13-acetate repressed protein 1; AI174028; C Cmotif chemokine; C x C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 12; chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1); CXC; CXC motif chemokine; C-X-C motif chemokine 12; C-X-C motif chemokine ligand 12; CXCL; Cxcl12; hIRH; hSDF-1; Intercrine reduced in hepatomas; IRH; PBSF; pre-B cell growth-stimulating factor; pre-B-cell growth-stimulating factor; Scyb12; Sdf1; SDF-1; SDF-1 gamma; SDF1A; SDF-1 A; SDF-1-alpha(3-67); SDF1B; SDF-1 b; SDF-1-beta(3-72); Stromal cell-derived factor 1; stromal cell-derived factor-1 alpha; stromal cell-derived factor-1 gamma; thymic lymphoma cell-stimulating factor; TLSF; Tlsfa; TLSF-a; Tlsfb; TLSF-b; Tpar1 | |
| ED50 = 50 - 100 ng/mL; determined by the dose-dependent chemotaxis of human PBMCs. | |
| Mouse | |
| KPVSLSYRCP CRFFESHIAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNKRL KM | |
| Carrier-Free | |
| Wet Ice | |
| Chemokines & Receptors | |
| Lyophilized | |
| Immunology, Stem Cell Research, Cardiovascular Research, Neurobiology | |
| >98% by SDS-PAGE |
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