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STEMCELL Technologies Mouse Recombinant IL-4

Interleukin 4

2471.14 SEK - 40725.93 SEK

Specifications

Name B cell stimulating factor, BCDF, BCGF, BSF-1, Interleukin-4
Cell Type B Cells; Dendritic Cells; Hematopoietic Stem and Progenitor Cells; Lymphocytes; Monocytes; Myeloid Cells; Neurons; T Cells
Purity or Quality Grade ≥95%
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Products 3
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
17179431
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STEMCELL Technologies
78047
100 μg
8146.25 SEK
100µg
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Estimated Shipment: 19-04-2024
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17189431
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STEMCELL Technologies
78047.1
20 μg
2471.14 SEK
20µg
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Estimated Shipment: 03-04-2024
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17199431
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STEMCELL Technologies
78047.2
1000 μg
40725.93 SEK
1000µg
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Estimated Shipment: 19-04-2024
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Description

Description

  • Interleukin 4 (IL-4) is a type I cytokine produced by Th2 T cells, NK T cells, γ/δ T cells, eosinophils, mast cells, and activated basophils
  • IL-4 receptors are present on a number of cells, including hematopoietic, endothelial, epithelial, muscle, and brain tissues
  • IL-4 receptor engagement initiates signaling through the JAK/STAT pathway, and leads to the activation of PI3K and Ras/MAPK pathways (Nelms et al.) IL-4 plays a key role in immunoglobulin class switching in B cells and in regulating the differentiation of naïve T cells into T helper 2 (Th2) cells, while inhibiting Th1 differentiation
  • IL-4 acts together with tumor necrosis factor to stimulate expression of adhesion molecules on vascular endothelial cells and to downregulate expression of E-selectin, thus recruiting T cells and eosinophils to the site of inflammation (Nelms et al.)
Specifications

Specifications

B cell stimulating factor, BCDF, BCGF, BSF-1, Interleukin-4
B Cells; Dendritic Cells; Hematopoietic Stem and Progenitor Cells; Lymphocytes; Monocytes; Myeloid Cells; Neurons; T Cells
≥95%
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