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STEMCELL Technologies Mouse Recombinant IL-4
Interleukin 4
2596.05 SEK - 42785.55 SEK
Specifications
| Name | B cell stimulating factor, BCDF, BCGF, BSF-1, Interleukin-4 |
|---|---|
| Cell Type | B Cells; Dendritic Cells; Hematopoietic Stem and Progenitor Cells; Lymphocytes; Monocytes; Myeloid Cells; Neurons; T Cells |
| Purity or Quality Grade | ≥95% |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
17179431
|
STEMCELL Technologies
78047 |
100 ÎĽg |
8557.65 SEK
100µg |
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|
17189431
|
STEMCELL Technologies
78047.1 |
20 ÎĽg |
2596.05 SEK
20µg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
|
17199431
|
STEMCELL Technologies
78047.2 |
1000 ÎĽg |
42785.55 SEK
1000µg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
- Interleukin 4 (IL-4) is a type I cytokine produced by Th2 T cells, NK T cells, γ/δ T cells, eosinophils, mast cells, and activated basophils
- IL-4 receptors are present on a number of cells, including hematopoietic, endothelial, epithelial, muscle, and brain tissues
- IL-4 receptor engagement initiates signaling through the JAK/STAT pathway, and leads to the activation of PI3K and Ras/MAPK pathways (Nelms et al.) IL-4 plays a key role in immunoglobulin class switching in B cells and in regulating the differentiation of naĂŻve T cells into T helper 2 (Th2) cells, while inhibiting Th1 differentiation
- IL-4 acts together with tumor necrosis factor to stimulate expression of adhesion molecules on vascular endothelial cells and to downregulate expression of E-selectin, thus recruiting T cells and eosinophils to the site of inflammation (Nelms et al.)
Specifications
| B cell stimulating factor, BCDF, BCGF, BSF-1, Interleukin-4 | |
| B Cells; Dendritic Cells; Hematopoietic Stem and Progenitor Cells; Lymphocytes; Monocytes; Myeloid Cells; Neurons; T Cells | |
| ≥95% |
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Product Title
STEMCELL Technologies Mouse Recombinant IL-4