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MPP8 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

1645.54 SEK - 4652.90 SEK

Specifications

Antigen MPP8
Concentration 0.31 mg/mL
Applications Western Blot, Immunoprecipitation
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16896534
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Proteintech
16796-1-AP-20UL
20 ÎĽL
1645.54 SEK
20µL
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16886534
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Proteintech
16796-1-AP-150UL
150 ÎĽL
4652.90 SEK
150µL
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Description

Description

Heterochromatin component that specifically recognizes and binds methylated ′Lys-9′ of histone H3 (H3K9me) and promotes recruitment of proteins that mediate epigenetic repression. Mediates recruitment of the HUSH complex to H3K9me3 sites: the HUSH complex is recruited to genomic loci rich in H3K9me3 and is probably required to maintain transcriptional silencing by promoting recruitment of SETDB1, a histone methyltransferase that mediates further deposition of H3K9me3. Binds H3K9me and promotes DNA methylation by recruiting DNMT3A to target CpG sites; these can be situated within the coding region of the gene. Mediates down-regulation of CDH1 expression.
Specifications

Specifications

MPP8
Western Blot, Immunoprecipitation
Unconjugated
Rabbit
Mouse, Rat, Human
G3V8T1, Q3TYA6, Q99549
290270, 54737, 75339
MPP8 Fusion Protein Ag10268
Primary
-20°C
MPHOSPH8
0.31 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
HSMPP8, M phase phosphoprotein 8, MPHOSPH8, MPP8, TWA3
Mphosph8
IgG
Antigen Affinity Chromatography
Antibody
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SDS
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Documents

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MPP8 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

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