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MPP8 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
1645.54 SEK - 4652.90 SEK
Specifications
Antigen | MPP8 |
---|---|
Concentration | 0.31 mg/mL |
Applications | Western Blot, Immunoprecipitation |
Classification | Polyclonal |
Conjugate | Unconjugated |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
16896534
|
Proteintech
16796-1-AP-20UL |
20 ÎĽL |
1645.54 SEK
20µL |
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16886534
|
Proteintech
16796-1-AP-150UL |
150 ÎĽL |
4652.90 SEK
150µL |
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Description
Heterochromatin component that specifically recognizes and binds methylated ′Lys-9′ of histone H3 (H3K9me) and promotes recruitment of proteins that mediate epigenetic repression. Mediates recruitment of the HUSH complex to H3K9me3 sites: the HUSH complex is recruited to genomic loci rich in H3K9me3 and is probably required to maintain transcriptional silencing by promoting recruitment of SETDB1, a histone methyltransferase that mediates further deposition of H3K9me3. Binds H3K9me and promotes DNA methylation by recruiting DNMT3A to target CpG sites; these can be situated within the coding region of the gene. Mediates down-regulation of CDH1 expression.Specifications
MPP8 | |
Western Blot, Immunoprecipitation | |
Unconjugated | |
Rabbit | |
Mouse, Rat, Human | |
G3V8T1, Q3TYA6, Q99549 | |
290270, 54737, 75339 | |
MPP8 Fusion Protein Ag10268 | |
Primary | |
-20°C | |
MPHOSPH8 |
0.31 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
HSMPP8, M phase phosphoprotein 8, MPHOSPH8, MPP8, TWA3 | |
Mphosph8 | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |
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Product Title
MPP8 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech