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Myopodin Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 25453-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16824035

  • 1236.20 SEK / 20µL
Estimated Shipment: 07-12-2021

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Description

Description

SYNPO2 was initially identified as myopodin, a member of the synaptopodin family that contains one PPXY motif and multiple PXXP motifs. It colocalizes with alpha-actinin and is found at the Z-disc and during stress conditions will translocate to the nucleus, suggesting that it is part of signaling pathways in addition to its function as a structural protein. SYNPO2 has been shown to bind to calmodulin, alpha-actinin, and smooth muscle myosin and will stimulate actin polymerization in a calmodulin dependent manner, consistent with its proposed role in organizing the cytoskeleton. While deletion of SYNPO2 has been reported to be highly correlated with the invasiveness of prostate cancers, other reports suggest that down-regulation of SYNPO2 reduces the invasiveness and motility of prostate cancer cells.
Specifications

Specifications

Myopodin
0.27 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
D4A702, Q91YE8, Q9UMS6
Genethonin 2, Myopodin, synaptopodin 2, SYNPO2
Rabbit
IgG
20 μL
-20°C
Primary
118449, 171024, 499702
Western Blot
Unconjugated
SYNPO2
Liquid
SYNPO2
Myopodin Fusion Protein Ag22176
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Mouse, Rat, Human
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Special Offers

Special Offers