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NEK3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 12843-1-AP-150UL
Additional Details : Weight : 0.00010kg
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DescriptionNIMA was originally shown in Aspergillus nidulans to be necessary for entry into mitosis. NIMA-related mammalian proteins have since been identified as Nek1, Nek2, Nek3 and Nek4 (also designated STK2 or NRK2). High expression of Nek1 is seen in male and female germ cell lines of mouse. Nek2 is the closest known mammalian relative to NIMA. Like NIMA, Nek2 expression peaks at the G2 to M phase transition. Nek3 is a predomitly cytoplasmic enzyme that was detectable in all organs studied. Levels of Nek3 seem to remain unchanged throughout the cell cycle, but appear to be elevated in G0-arrested, quiescent fibroblasts. In developing testicular germ cells, differential patterns of expression were seen for Nek1, Nek2 and Nek4, indicating possible overlapping, but non-identical functions.
|HSPK 36, HSPK36, NEK3, NimA related protein kinase 3|
|Antigen Affinity Chromatography|
|23954, 306576, 4752|
|Western Blot, Immunofluorescence, Immunocytochemistry|
|PBS with 50% glycerol and 0.1% sodium azide; pH 7.3|
|NEK3 Fusion Protein Ag3856|
|Rat, Mouse, Human|