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NUMB Mouse anti-Human, Mouse, Rat, Clone: 2G12B7, Proteintech
Mouse Monoclonal Antibody
1355.00 SEK - 3665.00 SEK
Specifications
Antigen | NUMB |
---|---|
Clone | 2G12B7 |
Concentration | 2 mg/mL |
Applications | Western Blot, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry |
Classification | Monoclonal |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
16887105
|
Proteintech
60137-1-IG-20UL |
20 μL |
1355.00 SEK
20µL |
Estimated Shipment: 29-04-2024 Log in to see stock. |
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16877105
|
Proteintech
60137-1-IG-150UL |
150 μL |
3665.00 SEK
150µL |
Estimated Shipment: 29-04-2024 Log in to see stock. |
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Description
Four transcript variants encoding different isoforms have been found for this gene. The antibody can bind to all these four isoforms P65, P66, P71, and P72, but can not recognize NUMBL.
Protein NUMB homolog is an evolutionarily conserved protein that controls the differentiation of neuronal progenitor cells. Recent studies have revealed that NUMB functions in clathrin-dependent endocytosis by binding to the AP-2 complex. NUMB is also expressed in postmitotic neurons and plays a role in axonal growth. Neural cells expressing Numb isoforms with short phosphotyrosine-binding (SPTB) domain undergo extensive neurite outgrowth, an effect that can be blocked by voltage-gated Ca2+ channel (VGCC) inhibitor or by Ca2+ chelator.Specifications
NUMB | |
2 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
h Numb, NUMB, numb homolog (Drosophila), Protein numb homolog, Protein S171, S171 | |
Numb | |
IgG2a | |
Caprylic Acid Precipitation | |
Antibody |
2G12B7 | |
Western Blot, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry | |
Unconjugated | |
Mouse | |
Mouse, Human, Rat | |
P49757, Q2LC84, Q9QZS3 | |
18222, 29419, 8650 | |
peptide | |
Primary | |
-20°C | |
NUMB |