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P glycoprotein Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 22336-1-AP-150UL
Additional Details : Weight : 0.00010kg
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DescriptionThe membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.
|ABCB1, CD243, GP170, MDR1, Multidrug resistance protein 1, P glycoprotein 1|
|Antigen Affinity Chromatography|
|18669, 18671, 5243|
|Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin)|
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|P06795, P08183, P21447|
|ABCB1, Abcb1a, Abcb1b|
|P glycoprotein Fusion Protein Ag17811|