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P-selectin Mouse anti-Human, Clone: 3G2C7, Proteintech
Mouse Monoclonal Antibody
Brand: Proteintech 60322-1-IG-20UL
Additional Details : Weight : 0.00010kg
Description
P-Selectin, also called CD62, GRMP, GMP140 is a 140-kD adhesion molecule, expressed at the surface of activated cells, that mediates the interaction of activated endothelial cells or platelets with leukocytes. The P-Selectin gene is mapped on 1q24.2. P-selectin plays an essential role in the initial recruitment of leukocytes (white blood cells) to the site of injury during inflammation. P-selectin is also very important in the recruitment and aggregation of platelets at areas of vascular injury. In quiescent platelet, P-selectin is located on the inner wall of alpha-granules. Sorting nexin-17 interacts with the cytosolic domain of P-selectin and suggested that SNX17 may function in the intracellular trafficking of P-selectin. P-selectin expression was found to be significantly and positively correlated with carotid artery stiffness and wall thickness, and the percentage of P-selectin-positive platelets was significantly higher in patients with carotid plaque.Specifications
P-selectin | |
Monoclonal | |
1.08 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
P16109 | |
SELP | |
P-selectin Fusion Protein Ag4124 | |
20 μL | |
Primary | |
Human | |
Antibody | |
IgG2b |
Immunoprecipitation, Western Blot, Immunohistochemistry (Paraffin) | |
3G2C7 | |
Unconjugated | |
SELP | |
CD62, CD62P, GMP 140, GMP140, GMRP, Granule membrane protein 140, GRMP, LECAM3, P selectin, PADGEM, PSEL, P-selectin, SELP | |
Mouse | |
Protein A | |
RUO | |
6403 | |
-20°C | |
Liquid |