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P-selectin Mouse anti-Human, Clone: 3G2C7, Proteintech
Mouse Monoclonal Antibody
Brand: Proteintech 60322-1-IG-20UL
Additional Details : Weight : 0.00010kg
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DescriptionP-Selectin, also called CD62, GRMP, GMP140 is a 140-kD adhesion molecule, expressed at the surface of activated cells, that mediates the interaction of activated endothelial cells or platelets with leukocytes. The P-Selectin gene is mapped on 1q24.2. P-selectin plays an essential role in the initial recruitment of leukocytes (white blood cells) to the site of injury during inflammation. P-selectin is also very important in the recruitment and aggregation of platelets at areas of vascular injury. In quiescent platelet, P-selectin is located on the inner wall of alpha-granules. Sorting nexin-17 interacts with the cytosolic domain of P-selectin and suggested that SNX17 may function in the intracellular trafficking of P-selectin. P-selectin expression was found to be significantly and positively correlated with carotid artery stiffness and wall thickness, and the percentage of P-selectin-positive platelets was significantly higher in patients with carotid plaque.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|P-selectin Fusion Protein Ag4124|
|Immunoprecipitation, Western Blot, Immunohistochemistry (Paraffin)|
|CD62, CD62P, GMP 140, GMP140, GMRP, Granule membrane protein 140, GRMP, LECAM3, P selectin, PADGEM, PSEL, P-selectin, SELP|