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DiscoverX PathHunter™ U2OS c-MET/c-MET Dimerization Cell Line
The PathHunter™ U2OS c-MET/c-MET Dimerization Cell Line measures ligand-induced dimerization of c-MET/c-MET . This cell line ships as two vials of cryopreserved cells.
Brand: DiscoverX 93-1063C3
This item is not returnable.
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Description
The PathHunter™ c-MET/c-MET Dimerization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This cell line enables assessment of ligand (e.g. hepatocyte growth factor) induced dimerization of c-MET/c-MET receptors. This product uses EFC technology. The cell line included overexpresses c-MET target protein fused to PK alongside c-MET target protein fused to EA. Upon ligand-induced dimerization of c-MET/c-MET , detectable EFC signal is produced. This stable modified cell line is provided as two vials of cryopreserved cells.Specifications
| Dimerization | |
| Cell Lines | |
| 2 Vials | |
| NM_000245.2 |
| U2OS | |
| Recombinant Human HGF | |
| c-MET/c-MET |
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Product Title
DiscoverX PathHunter™ U2OS c-MET/c-MET Dimerization Cell Line
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