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PD-L1/CD274 Mouse anti-Human, Mouse, Porcine, Rat, Clone: 2B11D11, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 66248-1-IG-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16887945

  • 1236.20 SEK / 20µL
Estimated Shipment: 02-12-2021

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Description

Description

PD-L1 (Programmed death receptor ligand 1, B7-H1, CD274) is a 40 kDa transmembrane protein and B7 family member. PD-L1 has been shown to negatively regulate T-cell receptor (TCR) signaling. Upon ligating its receptor, PD-L1 has been reported to decrease TCR-mediated proliferation and cytokine production, and PD-L1 expression was found to be abundant on many murine and human cancers and could be further up-regulated upon IFN-gamma stimulation. Thus, PD-L1 might play an important role in tumor immune evasion. Together with B7.1, PD-L1 can inactivate T cells and this relationship is a focal point of cancer therapeutic treatment. At least two isoforms of PDL-1 are known to exist.
Specifications

Specifications

PD-L1/CD274
2B11D11
Unconjugated
CD274
Liquid
CD274
PD-L1/CD274 Fusion Protein Ag12443
Protein G
RUO
Antibody
Monoclonal
Human, Porcine, Mouse, Rat
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunofluorescence, Flow Cytometry, Western Blot
1.55 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q9EP73, Q9NZQ7
B7 H, B7 H1, B7 homolog 1, B7H1, CD274, CD274 molecule, PD L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, PDL1, PD-L1, PD-L1/CD274, Programmed death ligand 1
Mouse
IgG1
20 μL
-20°C
Primary
29126, 499342, 574058, 60533
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Special Offers

Special Offers