missing translation for 'onlineSavingsMsg'
PD-L1/CD274 Mouse anti-Human, Mouse, Porcine, Rat, Clone: 2B11D11, Proteintech
Mouse Monoclonal Antibody
Brand: Proteintech 66248-1-IG-20UL
Additional Details : Weight : 0.00010kg
VideosSDSDocumentsCertificates Special Offers
DescriptionPD-L1 (Programmed death receptor ligand 1, B7-H1, CD274) is a 40 kDa transmembrane protein and B7 family member. PD-L1 has been shown to negatively regulate T-cell receptor (TCR) signaling. Upon ligating its receptor, PD-L1 has been reported to decrease TCR-mediated proliferation and cytokine production, and PD-L1 expression was found to be abundant on many murine and human cancers and could be further up-regulated upon IFN-gamma stimulation. Thus, PD-L1 might play an important role in tumor immune evasion. Together with B7.1, PD-L1 can inactivate T cells and this relationship is a focal point of cancer therapeutic treatment. At least two isoforms of PDL-1 are known to exist.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|PD-L1/CD274 Fusion Protein Ag12443|
|Rat, Mouse, Porcine, Human|
|Western Blot, Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunocytochemistry|
|B7 H, B7 H1, B7 homolog 1, B7H1, CD274, CD274 molecule, PD L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, PDL1, PD-L1, PD-L1/CD274, Programmed death ligand 1|
|29126, 499342, 574058, 60533|