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PELI1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

1645.54 SEK - 4652.90 SEK

Specifications

Antigen PELI1
Concentration 0.35 mg/mL
Applications Western Blot, Immunohistochemistry (Paraffin), Immunoprecipitation
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16899533
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Proteintech
12053-1-AP-20UL
20 ÎĽL
1645.54 SEK
20µL
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16889533
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Proteintech
12053-1-AP-150UL
150 ÎĽL
4652.90 SEK
150µL
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Description

Description

This antibody may cross react with Pellino-3.

The Pellino proteins are a highly homologous family of E3 ubiquitin ligases that act as upstream mediators in Toll-like receptor (TLR) pathways that lead to activation of MAP kinases and transcription factors. Pellino 1 is required for interleukin-1-mediated signaling through its interaction with the IRAK4-IRAK-TRAF6 complex, ultimately resulting in the activation of NF-Kappa-B. Like other members of the Pellino family, Pellino 1 is an E3 ubiquitin ligase, able to catalyze the polyubiquitination of IRAK1. It is activated via phosphorylation by either IRAK1 and IRAK4 or the IKK-related kinases IKK-epsilon; and TBK1. In addition to phosphorylation, Pellino 1 activity is also modulated via ubiquitination and sumoylation.
Specifications

Specifications

PELI1
Western Blot, Immunohistochemistry (Paraffin), Immunoprecipitation
Unconjugated
Rabbit
Rat, Mouse, Human
Q8C669, Q96FA3
305549, 57162, 67245
PELI1 Fusion Protein Ag2683
Primary
-20°C
PELI1
0.35 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
PELI1, Pellino 1, pellino homolog 1 (Drosophila), PRISM, Protein pellino homolog 1
PELI1
IgG
Antigen Affinity Chromatography
Antibody
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PELI1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

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