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PEX5 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 12545-1-AP-150UL
Additional Details : Weight : 0.00010kg
Description
This antibody recognizes endogenous PEX5, which migrates with an apparent molecular mass of 80 kDa.
The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified.Specifications
PEX5 | |
Polyclonal | |
Unconjugated | |
PEX5 | |
Peroxin 5, Peroxisome receptor 1, PEX5, PTS1 BP, PTS1 receptor, PTS1R, PXR1 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
19305, 312703, 5830 | |
-20°C | |
Liquid |
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation | |
0.19 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
O09012, P50542, Q2M2R8 | |
Pex5 | |
PEX5 Fusion Protein Ag3268 | |
150 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |