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PHIP Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 20933-1-AP-150UL
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Description
PHIP (pleckstrin homology domain interacting protein), also known as ndrp or WDR11, is a 1,821 amino acid protein that contains eight N-terminal WD40 repeats and two bromodomains. It is expressed in skeletal muscle (localizing to the cytosol and nucleus) and primary beta cells (localizing to the nucleus) and acts as a transcriptional activator. PHIP is known to interact with various members of the insulin receptor substrate (IRS) family. The IRS family of proteins mediate insulin receptor signaling and play an important role in insulin-producing beta cell proliferation and survival. PHIP specifically associates with the PH domain of IRS-1 and may function to link IRS-1 to insulin receptors, indicating a vital role of PHIP in the regulation of insulin signaling.Specifications
| PHIP | |
| Polyclonal | |
| Unconjugated | |
| PHIP | |
| ndrp, PH interacting protein, PHIP, WDR11 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 55023, 83946 | |
| -20°C | |
| Liquid |
| Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot | |
| 0.82 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| Q8VDD9, Q8WWQ0 | |
| PHIP | |
| PHIP Fusion Protein Ag14968 | |
| 150 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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Product Title
PHIP Rabbit anti-Human, Mouse, Polyclonal, Proteintech > 150 μL; Unconjugated
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