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PHIP Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 20933-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16880515

  • 4721.67 SEK / 150µL
Estimated Shipment: 14-05-2024
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Description

Description

PHIP (pleckstrin homology domain interacting protein), also known as ndrp or WDR11, is a 1,821 amino acid protein that contains eight N-terminal WD40 repeats and two bromodomains. It is expressed in skeletal muscle (localizing to the cytosol and nucleus) and primary beta cells (localizing to the nucleus) and acts as a transcriptional activator. PHIP is known to interact with various members of the insulin receptor substrate (IRS) family. The IRS family of proteins mediate insulin receptor signaling and play an important role in insulin-producing beta cell proliferation and survival. PHIP specifically associates with the PH domain of IRS-1 and may function to link IRS-1 to insulin receptors, indicating a vital role of PHIP in the regulation of insulin signaling.
Specifications

Specifications

PHIP
Polyclonal
Unconjugated
PHIP
ndrp, PH interacting protein, PHIP, WDR11
Rabbit
Antigen Affinity Chromatography
RUO
55023, 83946
-20°C
Liquid
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
0.82 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q8VDD9, Q8WWQ0
PHIP
PHIP Fusion Protein Ag14968
150 μL
Primary
Human, Mouse
Antibody
IgG
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