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PHLDA1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 18263-1-AP-150UL
Additional Details : Weight : 0.00010kg
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DescriptionCytotoxic T lymphocyte (CTL)-mediated cytotoxicity constitutes an important component of specific effector mechanisms in immunosurveillance against virus-infected or -transformed cells. Two mechanisms appear to account for this activity, one of which is the perforin-based process. Independently, a FAS-based mechanism involves the transducing molecule FAS (APO-1) and its ligand (FAS-L). The human FAS (APO-1) protein is a 48 kDa cell surface glycoprotein that belongs to a family of receptors that includes CD40, nerve growth factor receptors and tumor necrosis factor receptors. The FAS antigen is expressed on a broad range of lymphoid cell lines, and is expressed at high levels in T cells subsequent to crosslinking of the T cell receptor (TCR). A previously undescribed protein, TDAG51, restores activation- induced apoptosis in cells that have lost the ability to display Fas in response to activation.
|DT1P1B11, PHLDA1, PHRIP, PQ rich protein, PQR protein, TDAG51|
|Antigen Affinity Chromatography|
|21664, 22822, 29380|
|Western Blot, Immunofluorescence, Immunocytochemistry|
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|Q62392, Q8WV24, Q9QZA1|
|PHLDA1 Fusion Protein Ag13125|
|Rat, Mouse, Human|