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PHLDA1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 18263-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16888324

  • 3665.00 SEK / 150µL
Estimated Shipment: 31-03-2023
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Description

Description

Cytotoxic T lymphocyte (CTL)-mediated cytotoxicity constitutes an important component of specific effector mechanisms in immunosurveillance against virus-infected or -transformed cells. Two mechanisms appear to account for this activity, one of which is the perforin-based process. Independently, a FAS-based mechanism involves the transducing molecule FAS (APO-1) and its ligand (FAS-L). The human FAS (APO-1) protein is a 48 kDa cell surface glycoprotein that belongs to a family of receptors that includes CD40, nerve growth factor receptors and tumor necrosis factor receptors. The FAS antigen is expressed on a broad range of lymphoid cell lines, and is expressed at high levels in T cells subsequent to crosslinking of the T cell receptor (TCR). A previously undescribed protein, TDAG51, restores activation- induced apoptosis in cells that have lost the ability to display Fas in response to activation.
Specifications

Specifications

PHLDA1
Polyclonal
Unconjugated
PHLDA1
DT1P1B11, PHLDA1, PHRIP, PQ rich protein, PQR protein, TDAG51
Rabbit
Antigen Affinity Chromatography
RUO
21664, 22822, 29380
-20°C
Liquid
Western Blot, Immunofluorescence, Immunocytochemistry
0.19 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q62392, Q8WV24, Q9QZA1
Phlda1
PHLDA1 Fusion Protein Ag13125
150 μL
Primary
Rat, Mouse, Human
Antibody
IgG
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