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Invitrogen™ phospho-Tyrosine Monoclonal Antibody (pY20), PerCP-eFluor™ 710, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen™ 46-5001-42

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Product Code. 15569256

  • 4265.00 SEK / 100 tests

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Description

Description

The role of tyrosine phosphorylation in transduction of the mitogenic signal from transmembrane receptors and in transformation by oncogene tyrosine kinases has been the subject of intense investigation for several years. While the phosphorylation of specific tyrosine residues has been shown to be a primary mechanism of signal transduction during normal mitogenesis, cell cycle progression and oncogenic transformation, its role in other areas such as differentiation and gap junction communication, is a matter of active and ongoing research. Antibodies that specifically recognize phosphorylated tyrosine residues have proved to be invaluable to the study of tyrosine -phosphorylated proteins and the biochemical pathways in which they function. The fluorescein (FITC) conjugate of clone PY20 anti-phosphotyrosine is especially useful for the detection of these P-Tyr proteins in immunohistochemical and immunocytochemical protocols in situations wherein the use of a secondary antibody would complicate detection of the protein(s) of interest.

The role of tyrosine phosphorylation in transduction of the mitogenic signal from transmembrane receptors and in transformation by oncogene tyrosine kinases has been the subject of intense investigation for several years. While the phosphorylation of specific tyrosine residues has been shown to be a primary mechanism of signal transduction during normal mitogenesis, cell cycle progression and oncogenic transformation, its role in other areas such as differentiation and gap junction communication, is a matter of active and ongoing research. Antibodies that specifically recognize phosphorylated tyrosine residues have proved to be invaluable to the study of tyrosine -phosphorylated proteins and the biochemical pathways in which they function. The fluorescein (FITC) conjugate of clone PY20 anti-phosphotyrosine is especially useful for the detection of these P-Tyr proteins in immunohistochemical and immunocytochemical protocols in situations wherein the use of a secondary antibody would complicate detection of the protein(s) of interest.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

phospho-Tyrosine
Monoclonal
5 ÎĽL/Test
PBS with BSA and 0.09% sodium azide; pH 7.2
Mouse
100 Tests
Primary
4°C, store in dark, DO NOT FREEZE!
Liquid
Chemical
Flow Cytometry
pY20
PerCP-eFluor 710
Phosphotyrosine; pTyr; pY
Affinity chromatography
RUO
Chemical
Antibody
IgG2b Îş
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Product Title
Invitrogen™ phospho-Tyrosine Monoclonal Antibody (pY20), PerCP-eFluor™ 710, eBioscience™, Invitrogen™ > 100 Tests; PerCP-eFluor 710

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