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Invitrogen™ Human PI4K2B (PI4K2 beta), GST Tag Recombinant Protein Product Code.: 15960313

Invitrogen™ Human PI4K2B (PI4K2 beta), GST Tag Recombinant Protein

Product Code. 15960313
20 μg, 20µg
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Quantity:
1 mg
100 μg
20 μg
Unit Size:
100µg
1mg
20µg
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Product Code. 15960313

Brand: Invitrogen™ A31080

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Recombinant Protein

PI4K2B lipid kinase is a member of the phosphatidylinositol 4-kinase family (PI4K) that phosphorylate phosphatidylinositol to generate phosphatidylinositol 4-phosphate which are immediate precursor of several important signaling and scaffolding molecules. PI4K2B is primarily a cytosolic PI4K that is recruited to membranes where it stimulates phosphatidylinositol 4,5-bisphosphate syntheses. PI4K2B uses phosphatidylinositol as its primary substrate and has no activity on phosphatidylinositol monophosphates. PI4K2B is a restricted minor histocompatibility antigen in patients that had been successfully treated with donor lymphocyte infusions for relapsed chronic myeloid leukemia after allogeneic stem cell transplantation. Phosphatidylinositol 4-kinases (PI4Ks) phosphorylate phosphatidylinositol to generate phosphatidylinositol 4-phosphate (PIP), an immediate precursor of several important signaling and scaffolding molecules. PIP itself may also have direct functional and structural roles. PI4K2B is a primarily cytosolic PI4K that is recruited to membranes, where it stimulates phosphatidylinositol 4, 5-bisphosphate synthesis (Wei et al., 2002 ).
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q8TCG2
Concentration See Label
For Use With (Application) Kinase Assay
Formulation 50 mM tris HCl with 0.1 mM EDTA, 0.1 mM PMSF, 0.25 mM DTT, 10 mM glutathione, 150 mM NaCl, 25% glycerol and no preservative; pH 7.5
Gene ID (Entrez) 55300
Molecular Weight (g/mol) 82.1 kDa
Name Human PI4K2B (PI4K2 beta), GST Tag
Quantity 20 μg
Gene Alias 2610042N09Rik; 4933409G22Rik; hypothetical protein; phosphatidylinositol 4-kinase; phosphatidylinositol 4-kinase type 2 beta; Phosphatidylinositol 4-kinase type 2 beta; Phosphatidylinositol 4-kinase type 2-beta; phosphatidylinositol 4-kinase type 2-beta; Phosphatidylinositol 4-kinase type II-beta; phosphatidylinositol 4-kinase type-II beta; PI4K2B; PI4K2B protein; PI4KIIB; PI4KII-BETA; PIK42B; RCJMB04_25j21
Common Name PI4K2B
KinaseFamily PI3 Kinase
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag GST-tag
Sequence Full length
Content And Storage -80°C, Avoid Freeze/Thaw Cycles
Shipping Condition Dry Ice
Expression System Insect cells
Protein Family Kinases & Inhibitors
Protein Form Full Length, Recombinant, Active
Form Liquid
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