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Thermo Scientific™ Pierce™ SMCC

Product Code. 10066813 Shop All Thermo Scientific Products
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Quantity:
50 mg
10 x 1 mg
Unit Size:
50mg
Pack of 10
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Product Code. Quantity Unit Size
10066813 50 mg 50mg
15890853 10 x 1 mg Pack of 10
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Product Code. 10066813 Supplier Thermo Scientific™ Supplier No. 22360
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Description

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Thermo Scientific™ Pierce SMCC is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a medium-length cyclohexane-stabilized spacer arm (8.3 Ås).

Highlights:

  • Cyclohexane bridge adds stability to the maleimide-reactive group; N-(4-carboxycyclohexylmethyl) maleimide groups are stable for 64 hours in 0.1 M sodium phosphate buffer, pH 7.0 at 4°C
  • Ideal for coupling enzymes to antibodies
  • Reactive groups: NHS-ester and maleimide
  • Reactive toward: amino and sulfhydryl groups
TRUSTED_SUSTAINABILITY

Spécification

Chemical Reactivity Amine-Sulfhydryl
Cleavable By Thiols
Molecular Weight (g/mol) 334.32
PEGylated No
Spacer Arm Length 8.3 Å
Content And Storage Upon receipt store desiccated at 4°C.
Cell Permeability Yes
Shipping Condition Ambient
Product Line Pierce
Labeling Method Chemical Labeling
Crosslinker Type Heterobifunctional
Reactive Moiety Maleimide, NHS Ester
Spacer Short (<10 Å)
Form Powder
Quantity 50 mg
Solubility DMF, DMSO
Format Standard, Single-use
Water Soluble No
Product Type Crosslinker
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Safety and Handling

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Identifiant produit
  • SMCC
 Mention d'avertissement
  • Warning
 Catégorie de danger
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3
 Mention de danger
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H335-May cause respiratory irritation.
 Conseils de prudence
  • P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P264-Wash hands thoroughly after handling.
  • P271-Use only outdoors or in a well-ventilated area.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P312-Call a POISON CENTER/doctor/if you feel unwell.
  • P332+P313-If skin irritation occurs: Get medical advice/attention.
  • P337+P313-If eye irritation persists: Get medical advice/attention.
  • P362+P364-Take off contaminated clothing and wash it before reuse.
  • P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
 Informations supplémentaires
  • MIXTURE LIST-Contain: Succinimidyl-trans-4-(N-maleimidylmethyl)cyclohexane-1-carboxylate

For Research Use Only. Not for use in diagnostic procedures.

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