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PLOD2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 21214-1-AP-150UL

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Product Code. 16880835

  • 4652.90 SEK / 150µL

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Description

Description

This antibody is specific to PLOD2.

The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.
Specifications

Specifications

PLOD2
Polyclonal
Unconjugated
PLOD2
LH2, Lysyl hydroxylase 2, PLOD2-Specific, TLH
Rabbit
Antigen Affinity Chromatography
RUO
26432, 300901, 5352
-20°C
Liquid
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
0.21 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O00469, Q811A3, Q9R0B9
PLOD2
PLOD2-Specific Fusion Protein Ag15614
150 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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Product Title
PLOD2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech > 150 μL; Unconjugated

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