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PPM1F Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 17020-1-AP-150UL
Additional Details : Weight : 0.00010kg
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DescriptionPPM1F is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis.
|CaM kinase phosphatase, CaMKPase, FEM 2, hFEM 2, KIAA0015, Partner of PIX 2, POPX2, PPM1F, Protein fem 2 homolog, Protein phosphatase 1F|
|Antigen Affinity Chromatography|
|287931, 68606, 9647|
|Western Blot, Immunoprecipitation, Immunofluorescence, Immunocytochemistry|
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|P49593, Q8CGA0, Q9WVR7|
|PPM1F Fusion Protein Ag10186|
|Rat, Mouse, Human|