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PRAS40 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 21097-1-AP-150UL
Additional Details : Weight : 0.00010kg
Description
The Akt signaling pathway contributes to the regulation of apoptosis after a variety of cell death signals. AKT1S1, also known as PRAS40, is a proline-rich substrate of the kinase AKT1 and is thought to play a role in neuroprotection mediated by nerve growth factor (NGF) after transient focal cerebral ischemia. AKT1S1 is also a substrate and potential regulator of mammalian target of rapamycin (mTOR), a serine/threonine kinase that regulates cell growth and cell cycle, and a negative regulator of autophagy. Treatment with the insulin-like growth factor-1 (IGF1) can indusce the phosphorylation of AKT1S1 via the PI3K/AKT signaling pathway in PC12 cells.Specifications
| PRAS40 | |
| Polyclonal | |
| Unconjugated | |
| AKT1S1 | |
| AKT1S1, AKTS1, Lobe, PRAS40, Proline rich AKT1 substrate 1 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 84335 | |
| -20°C | |
| Liquid |
| Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot | |
| 0.81 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| Q96B36 | |
| AKT1S1 | |
| PRAS40 Fusion Protein Ag15355 | |
| 150 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |