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PrP Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
1645.54 SEK - 4652.90 SEK
Specifications
Antigen | PrP |
---|---|
Concentration | 0.25 mg/mL |
Applications | Immunohistochemistry (Paraffin), Western Blot, Flow Cytometry, Immunoprecipitation |
Classification | Polyclonal |
Conjugate | Unconjugated |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
16890314
|
Proteintech
12555-1-AP-20UL |
20 ÎĽL |
1645.54 SEK
20µL |
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16880314
|
Proteintech
12555-1-AP-150UL |
150 ÎĽL |
4652.90 SEK
150µL |
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Description
Human prion protein (PrP), also known as PRNP, is a ubiquitously expressed GPI-anchored cell surface glycoprotein associating with lipid raft components and functioning as a signaling molecule. PrP plays a role in apoptosis in a cell context-dependent manner, is involved in proliferation of epithelial cells and in distribution of junction-associated proteins in human enterocytes. Conversion of this normal cellular prion protein (PrPc) into an abnormal conformer (PrPSc) is the crucial step associated with triggering the pathogenesis of the prion neurodegenerative disorders, such as the Creutzfeld-Jakob disease (CJD). Whereas PrPc is rich in alpha-helices, the PrPSc form has higher content of beta-sheets and is resistant to proteinase K.Specifications
PrP | |
Immunohistochemistry (Paraffin), Western Blot, Flow Cytometry, Immunoprecipitation | |
Unconjugated | |
Rabbit | |
Human, Mouse, Rat | |
F7VJQ1, P04925, P13852 | |
19122, 24686, 5621 | |
PrP Fusion Protein Ag3257 | |
Primary | |
-20°C | |
PRNP |
0.25 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
ASCR, CD230, CJD, GSS, Major prion protein, prion, prion protein, PRIP, PRNP, PrP, PrP27 30, PrP33 35C, PrPc | |
Prnp | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |
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Product Title
PrP Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech