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PSMD2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 14748-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16823554

  • 1236.20 SEK / 20µL
Estimated Shipment: 07-12-2021

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Description

Description

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. In addition to participation in proteasome function, this subunit may also participate in the TNF signalling pathway since it interacts with the tumor necrosis factor type 1 receptor. A pseudogene has been identified on chromosome 1.
Specifications

Specifications

PSMD2
0.21 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q13200, Q4FZT9, Q8VDM4
26S proteasome subunit p97, P97, Protein 55.11, PSMD2, Rpn1, S2, TRAP2
Rabbit
IgG
20 μL
-20°C
Primary
21762, 287984, 5708
Immunofluorescence, Western Blot, Immunocytochemistry, Immunoprecipitation
Unconjugated
PSMD2
Liquid
Psmd2
PSMD2 Fusion Protein Ag6484
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Mouse, Human, Rat
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