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PTBP1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 12582-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16840364

  • 3665.00 SEK / 150µL
Estimated Shipment: 06-12-2022
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Description

Description

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has four repeats of quasi-RNA recognition motif (RRM) domains that bind RNAs. This protein binds to the intronic polypyrimidine tracts that requires pre-mRNA splicing and acts via the protein degradation ubiquitin-proteasome pathway. It may also promote the binding of U2 snRNP to pre-mRNAs. This protein is localized in the nucleoplasm and it is also detected in the perinucleolar structure. Alternatively spliced transcript variants encoding different isoforms have been described.
Specifications

Specifications

PTBP1
Polyclonal
Unconjugated
PTBP1
HNRNP I, HNRNPI, HNRPI, pPTB, PTB, PTB 1, PTB T, PTB2, PTB3, PTB4, PTBP1
Rabbit
Antigen Affinity Chromatography
RUO
19205, 29497, 5725
-20°C
Liquid
Western Blot, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry
0.25 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P17225, P26599, Q00438
Ptbp1
PTBP1 Fusion Protein Ag3277
150 μL
Primary
Rat, Mouse, Human
Antibody
IgG
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