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PTGDS Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 10754-2-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16877343

  • 1236.20 SEK / 20µL
Estimated Shipment: 07-12-2021

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Description

Description

The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. PTGDS has also been implicated in the development and maintece of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement (NREM) sleep. It is likely to play important roles in both maturation and maintece of the central nervous system and male reproductive system. PTGDS is the most abundant protein in the cerebral spinal fluid and recent evidence suggests that PTGDS acts as a Beta-Amyloid chaperone and may have a role in the deposition of Ab plaques in Alzheimer′s disease.
Specifications

Specifications

PTGDS
0.13 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P41222
Beta trace protein, Cerebrin 28, LPGDS, PDS, PGD2, PGD2 synthase, PGDS, PGDS2, Prostaglandin D2 synthase, Prostaglandin H2 D isomerase, PTGDS
Rabbit
IgG
20 μL
-20°C
Primary
5730
Western Blot, Immunohistochemistry (Paraffin)
Unconjugated
PTGDS
Liquid
PTGDS
PTGDS Fusion Protein Ag1163
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
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