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PTP4A1/PRL1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 11508-1-AP-150UL
Additional Details : Weight : 0.00010kg
Description
The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This tyrosine phosphatase is a nuclear protein, but may primarily associate with plasma membrane. The surface membrane association of this protein depends on its C-terminal prenylation. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which implicated its role in the tumorigenesis. Studies in rat suggested that this gene may be an immediate-early gene in mitogen-stimulated cells. PRL phosphatases increase cell proliferation by stimulating progression from G1 into S phase. PRL-1 function is regulated in a cell cycle-dependent manner and implicate PRL-1 in regulating progression through mitosis, possibly by modulating spindle dynamics.Specifications
PTP4A1/PRL1 | |
Polyclonal | |
Unconjugated | |
PTP4A1 | |
HH72, PRL 1, PRL1, PTP(CAAX1), PTP(CAAXI), PTP4A1, PTPCAAX1 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
19243, 29463, 7803 | |
-20°C | |
Liquid |
Western Blot, Immunohistochemistry (Paraffin) | |
0.23 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
Q63739, Q78EG7, Q93096 | |
PTP4A1 | |
PTP4A1/PRL1 Fusion Protein Ag2067 | |
150 μL | |
Primary | |
Rat, Mouse, Human | |
Antibody | |
IgG |