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RanGAP1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 27405-1-AP-20UL
Additional Details : Weight : 0.00010kg
Description
RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1, 000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGAP1 gene encodes a 587-amino acid polypeptide. The sequence is unrelated to that of GTPase activators for other RAS-related proteins, but is 88% identical to Fug1, the murine homolog of yeast Rna1p. RanGAP1 and RCC1 control RAN-dependent transport between the nucleus and cytoplasm. RanGAP1 is a key regulator of the RAN GTP/GDP cycle.Specifications
| RanGAP1 | |
| Polyclonal | |
| Unconjugated | |
| RANGAP1 | |
| Fug1, KIAA1835, RANGAP1, SD | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 19387, 5905 | |
| -20°C | |
| Liquid |
| Western Blot | |
| 0.37 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| P46060, P46061 | |
| RANGAP1 | |
| RanGAP1 Fusion Protein Ag26128 | |
| 20 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |