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RanGAP1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 27405-1-AP-20UL
Additional Details : Weight : 0.00010kg
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DescriptionRanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1, 000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGAP1 gene encodes a 587-amino acid polypeptide. The sequence is unrelated to that of GTPase activators for other RAS-related proteins, but is 88% identical to Fug1, the murine homolog of yeast Rna1p. RanGAP1 and RCC1 control RAN-dependent transport between the nucleus and cytoplasm. RanGAP1 is a key regulator of the RAN GTP/GDP cycle.
|Fug1, KIAA1835, RANGAP1, SD|
|Antigen Affinity Chromatography|
|PBS with 50% glycerol and 0.1% sodium azide; pH 7.3|
|RanGAP1 Fusion Protein Ag26128|