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RanGAP1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 27405-1-AP-20UL

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Product Code. 16885605

  • 1645.54 SEK / 20µL

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Description

Description

RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1, 000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGAP1 gene encodes a 587-amino acid polypeptide. The sequence is unrelated to that of GTPase activators for other RAS-related proteins, but is 88% identical to Fug1, the murine homolog of yeast Rna1p. RanGAP1 and RCC1 control RAN-dependent transport between the nucleus and cytoplasm. RanGAP1 is a key regulator of the RAN GTP/GDP cycle.
Specifications

Specifications

RanGAP1
Polyclonal
Unconjugated
RANGAP1
Fug1, KIAA1835, RANGAP1, SD
Rabbit
Antigen Affinity Chromatography
RUO
19387, 5905
-20°C
Liquid
Western Blot
0.37 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P46060, P46061
RANGAP1
RanGAP1 Fusion Protein Ag26128
20 μL
Primary
Mouse, Human
Antibody
IgG
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RanGAP1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech > 20 μL; Unconjugated

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