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RBBP8 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
1656.73 SEK - 4721.67 SEK
Specifications
Antigen | RBBP8 |
---|---|
Concentration | 0.13 mg/mL |
Applications | Western Blot |
Classification | Polyclonal |
Conjugate | Unconjugated |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
16890434
|
Proteintech
12624-1-AP-20UL |
20 μL |
1656.73 SEK
20µL |
Estimated Shipment: 22-04-2024 Log in to see stock. |
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16880434
|
Proteintech
12624-1-AP-150UL |
150 μL |
4721.67 SEK
150µL |
Estimated Shipment: 22-04-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
CtIP, a 125 kD protein, was originally found interacting with a transcription repressor, CtBP, through the PLDLS motif (CtBP-Interacting Protein) thus suggested a role in transcription. Studies have shown that CtIP also interacts with BRCA1 protein through the c-terminus BRCT domains also suggested that CtIP is a potential tumor suppressor. This CtIP-BRCA1 interaction can be disruppted by DNA damaging agents including UV or gamma-irradiation. Li et al (Nature 406, 210 - 215 (2000)) have shown that ATM phosphorylates CtIP at serine residues 664 and 745, and mutation of these sites abrogates the dissociation of BRCA1 from CtIP, resulting in persistent repression of BRCA1-dependent induction of GADD45 upon ionizing radiation.Specifications
RBBP8 | |
Western Blot | |
Unconjugated | |
Rabbit | |
Mouse, Rat, Human | |
B1WC58, Q80YR6, Q99708 | |
225182, 291787, 5932 | |
RBBP8 Fusion Protein Ag3314 | |
Primary | |
-20°C | |
RBBP8 |
0.13 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
CtBP interacting protein, CTIP, DNA endonuclease RBBP8, RBBP 8, RBBP8, RIM, SAE2 | |
Rbbp8 | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |