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R&D Systems™ Recombinant Human TNF-alpha Hyperactive Mutant Protein Product Code.: 18747766
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R&D Systems™ Recombinant Human TNF-alpha Hyperactive Mutant Protein

Product Code. 18747766
100 μg, 25µg
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Quantity:
100 μg
25 μg
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25µg
This item is not returnable. View return policy

Product Code. 18747766

Brand: R&D Systems™ 8599TA100/CF

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3620.00 SEK valid until 2025-07-30
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This item is not returnable. View return policy

Description

Mutant form with approximately 5-fold greater activity

  • Measured in a cytotoxicity assay using L-929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D.
  • ED50 for this effect is 20 to 100 pg/mL.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P01375
For Use With (Application) Bioactivity
Gene ID (Entrez) 7124
Molecular Weight (g/mol) 17 kDa
Name APC1 protein, Cachectin, Cachetin, DIF, TNF, TNF, monocyte-derived, TNF-a, TNFA, TNFalpha, TNF-alphacachectin, TNFATNF, macrophage-derived, TNFG1F, TNFSF1A, TNFSF2, TNFSF2TNF superfamily, member 2, tumor necrosis factor, tumor necrosis factor (TNF superfamily, member 2), tumor necrosis factor alpha, Tumor necrosis factor ligand superfamily member 2, tumor necrosis factor-alpha
Quantity 100 μg
Source E. coli-derived human TNF-alpha protein Lys87-Leu233 (Leu233Phe), with an N-terminal Met-Arg-Lys-Arg
Storage Requirements Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
Gene Symbol TNF
Conjugate Unconjugated
Species Human
Reconstitution Reconstitute at 100 μg/mL in PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS.
Endotoxin Level <0.10 EU per 1 μg of the protein by the LAL method.
Purity or Quality Grade >95%, by SDS-PAGE with silver staining.
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